Gangrene

Tissue death from loss of blood flow or severe infection

Definition

Gangrene is the death (necrosis) of body tissue, usually from lack of blood flow or serious bacterial infection. It is a medical emergency requiring urgent intervention.

Types

  • Dry gangrene: Gradual loss of blood flow; tissue becomes dry, black, mummified, such as common in diabetes, PAD.
  • Wet gangrene: Bacterial infection with pus and foul odor; rapidly progresses.
  • Gas gangrene (clostridial myonecrosis): Life-threatening Clostridium perfringens infection with gas production in tissue, such as crepitus, severe pain, rapid progression.
  • Fournier gangrene: Necrotizing fasciitis of perineum.

Nursing Interventions

Monitor wounds in high-risk patients (diabetes, PAD). Administer IV antibiotics (broad-spectrum), provide wound care, prepare for surgical debridement or amputation. Hyperbaric oxygen for gas gangrene. Sepsis monitoring.

NCLEX Relevance

Gas gangrene is a surgical emergency with crepitus and rapidly progressing pain. Diabetes + foot wound is a classic setup.